Here, we demonstrate that conolidine, a purely natural analgesic alkaloid used in regular Chinese medication, targets ACKR3, thus supplying further evidence of the correlation between ACKR3 and suffering modulation and opening option therapeutic avenues to the procedure of chronic pain. Normal discomfort reduction without opioids, no Uncomfortable side effects? https://social4geek.com/story5347542/what-is-conolidine-for-dummies