And lastly, clonidine enhances neuraxial opioids and, together with fentanyl, interacts within an additive way, which could lessen the dose of each and every component by 60% for postoperative analgesia. For those who get dizzy when standing: This issue is called orthostatic hypotension. Clonidine could make this issue worse. https://lukasiaqlg.total-blog.com/onolidine-fundamentals-explained-57418732