Coadministration of encorafenib with delicate CYP3A4 substrates may result in amplified toxicity or diminished efficacy of these agents. diazepam will increase the amount or influence of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. If coadministration of lonafarnib (a delicate CYP3A substrate) with weak http://galenika bensedin 10mg diazepam