Hallucinogens/psychedelics may also be connected with novel mechanisms of action in relation to conventional drugs, which can be often based on the monoaminergic imbalance concept. The modulation of cortical 5-HT2A receptors and the subsequent rise in glutamatergic tone along with the connected neuroplasticity are novel mechanisms of action.seven,forty one,60 The https://www.evernote.com/shard/s719/sh/330863cc-f66e-28c9-1f41-da0804b81796/RMpoTb0riW3RmWT16RjoS367Hafssl_5BT2tyYmOPBlf01wp-Yuv0jPVlw