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RANKL is actually a member with the tumor necrosis component (TNF) cytokine loved ones, it binds to RANK on cells on the myeloid lineage and features like a essential issue for osteoclast differentiation and activation. RANKL could also bind to osteoprotegerin, a protein secreted mainly by cells of your osteoblast http://rank12333.ka-blogs.com/47676401/5-essential-elements-for-rank

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