RANKL is actually a member with the tumor necrosis element (TNF) cytokine loved ones, it binds to RANK on cells of the myeloid lineage and capabilities as a key factor for osteoclast differentiation and activation. RANKL may bind to osteoprotegerin, a protein secreted mainly by cells in the osteoblast lineage http://rank94335.jaiblogs.com/20317229/top-latest-five-rank-urban-news