Ongoing substance use Inspite of having persistent or recurrent social or interpersonal issues prompted or exacerbated by the results on the substance (e.g., arguments with husband or wife about penalties of intoxication, Actual physical fights) [13][fourteen] Long-term use of certain substances causes a transform inside the central nervous procedure often http://hectoriqyek.blogpostie.com/15071182/substance-abuse-list-for-dummies